TRILITE

Different series are applied according to the molecular size and polarity of the target substance. HP20 and the GSH-20 series are used for high-molecular-weight substances such as proteins; SP825, SP850, and the GSP-25 and GSP-50 series for the separation and purification of antibiotics including cephalosporin C; and SP207 and the GSP-07 series, with smaller pore sizes, for high-purity purification processes including semiconductor chemicals. Even among polystyrene-based adsorbents, specific surface area and pore size differ, so the general rule is to select based on the molecular weight of the target substance.

• Large-molecule adsorption : HP20 and GSH-20 series — proteins, high-molecular-weight substances
• Medium-molecule adsorption : SP825, SP850 and GSP-25, GSP-50 series — antibiotics, fermentation products
• Small-molecule / high purity : SP207 and GSP-07 series — including semiconductor chemicals

Because target substances are separated from fermentation broth by physical adsorption without chemical reactions, impurities can be removed without altering the structure of the substance. Adsorption and desorption are reversible,
so target substances can be selectively recovered by adjusting solvent conditions, contributing to higher purity and recovery. They can also be regenerated and reused, which is advantageous in terms of process cost.

• Applications: Fermentation broth purification, natural extract separation,
  decolorization and deodorization
• Desorption conditions: Use of organic solvents such as methanol and ethanol,
  or pH adjustment